Small-molecule inhibition of METTL3 as a strategy against myeloid leukaemia

Eliza Yankova, Wesley Blackaby, Mark R. Albertella, +22

Nature

Hematological MalignancyTumor BiologyMedicineMixed-phenotype Acute LeukemiaMalignant Blood Disorder +7

High-Resolution Analysis of Coronavirus Gene Expression by RNA Sequencing and Ribosome Profiling

Nerea Irigoyen, Andrew E. Firth, Joshua D. Jones, +3

PLoS Pathogens

Viral EvolutionFunctional GenomicsMedicineViral PathogenesisImmunology +12

The use of duplex-specific nuclease in ribosome profiling and a user-friendly software package for Ribo-seq data analysis

Betty Chung, Thomas J. Hardcastle, Joshua D. Jones, +4

RNA

Profiling MethodologiesGeneticsMolecular BiologyTranscriptomics TechnologyGenomics +17

An upstream protein-coding region in enteroviruses modulates virus infection in gut epithelial cells

Valeria Lulla, Adam M. Dinan, Myra Hosmillo, +8

Nature Microbiology

Gut Epithelial CellsMolecular VirologyMedicinePathogenesisViral Pathogenesis +7

Manipulation of the unfolded protein response: A pharmacological strategy against coronavirus infection

Liliana Echavarría-Consuegra, Georgia M. Cook, Idoia Busnadiego, +13

PLoS Pathogens

Viral ReplicationViral Polymerase MechanismViral PathogenesisImmunologyAntiviral Drug +19

Autoproteolytic Activity Derived from the Infectious Bursal Disease Virus Capsid Protein

Nerea Irigoyen, Damià Garriga, Aitor Navarro, +3

Journal of Biological Chemistry

Hybrid Gene Origination Creates Human-Virus Chimeric Proteins during Infection

Jessica Ho, Matthew Angel, Yixuan Ma, +51

Cell

Mechanical Stability and Reversible Fracture of Vault Particles

Aida Llauró, Pablo Guerra, Nerea Irigoyen, +3

Biophysical Journal

EngineeringPhysicsMechanicsImpact LoadingMechanical Engineering +6

Electrostatic Interactions between Capsid and Scaffolding Proteins Mediate the Structural Polymorphism of a Double-stranded RNA Virus

Irene Saugar, Nerea Irigoyen, Daniel Luque, +3

Journal of Biological Chemistry

Virus StructureViral ReplicationDouble-stranded Rna VirusNatural SciencesStructural Polymorphism +8

Host Proteolytic Activity Is Necessary for Infectious Bursal Disease Virus Capsid Protein Assembly

Nerea Irigoyen, José R. Castón, José F. Rodrígúez

Journal of Biological Chemistry

Virus StructureViral ReplicationMolecular VirologyMedicineNatural Sciences +5