Brendon Ladd

KDM4A Lysine Demethylase Induces Site-Specific Copy Gain and Rereplication of Regions Amplified in Tumors

Joshua C. Black, Amity L. Manning, Capucine Van Rechem et al. · Cell · 2013 · 212 citations · Full text

Tumor Biology, Health Sciences, Tumor Heterogeneity +10

AZD9496: An Oral Estrogen Receptor Inhibitor That Blocks the Growth of ER-Positive and <i>ESR1</i> -Mutant Breast Tumors in Preclinical Models

Hazel M. Weir, Robert H. Bradbury, Mandy Lawson et al. · Cancer Research · 2016 · 174 citations

Hypoxia drives transient site-specific copy gain and drug-resistant gene expression

Joshua C. Black, Elnaz Atabakhsh, Jaegil Kim et al. · Genes & Development · 2015 · 81 citations · Full text

Regulation of Tissue-Specific and Extracellular Matrix-Related Genes by a Class I Histone Deacetylase

Johnathan R. Whetstine, Julián Cerón, Brendon Ladd et al. · Molecular Cell · 2005 · 76 citations · Full text

Histone Modifications, Chromatin, Systems Biology +12

Tumors with AKT1E17K Mutations Are Rational Targets for Single Agent or Combination Therapy with AKT Inhibitors

Barry R. Davies, Nin Guan, Armelle Logié et al. · Molecular Cancer Therapeutics · 2015 · 70 citations