O. Klein

Weekly high-dose leucovorin versus low-dose leucovorin combined with fluorouracil in advanced colorectal cancer: results of a randomized multicenter trial. Study Group for Palliative Treatment of Metastatic Colorectal Cancer Study Protocol 1.

Elke Jäger, Michael Heike, H. Bernhard et al. · Journal of Clinical Oncology · 1996 · 120 citations

Medicine, Oncology, Pharmacology +17

Treatment of advanced pancreatic cancer with 5-fluorouracil, folinic acid and interferon alpha-2A: results of a phase II trial

H. Bernhard, E Jäger-Arand, Gudrun Bernhard et al. · British Journal of Cancer · 1995 · 43 citations · Full text

Medicine, Oncology, Pharmacology +12

Irinotecan plus folinic acid/continuous 5-fluorouracil as simplified bimonthly FOLFIRI regimen for first-line therapy of metastatic colorectal cancer

Andreas Teufel, Silke Steinmann, Jürgen Siebler et al. · BMC Cancer · 2004 · 33 citations · Full text

Medicine, Oncology, Pharmacotherapy +15

Second-Line Treatment with High-Dose 5-Fluorouracil and Folinic Acid in Advanced Colorectal Cancer Refractory to Standard-Dose 5-Fluorouracil Treatment

Elke Jäger, O. Klein, B. Wächter et al. · Oncology · 2009 · 17 citations

Medicine, Oncology, Pharmacotherapy +14

Safety and efficacy of outpatient treatment with CPT-11 plus bolus folinic acid/5-fluorouracil as first-line chemotherapy for metastatic colorectal cancer

Markus Moehler, Tanja Hoffmann, C. Zanke et al. · Anti-Cancer Drugs · 2003 · 16 citations

Medicine, Oncology, Pharmacology +14