Cucurbitacin B Induces Apoptosis by Inhibition of the <i>JAK/STAT</i> Pathway and Potentiates Antiproliferative Effects of Gemcitabine on Pancreatic Cancer Cells

Nils H. Thoennissen, Gabriela B. Iwanski, Ngan Doan, +8

Cancer Research

FOXO3a-dependent regulation of Pink1 (Park6) mediates survival signaling in response to cytokine deprivation

Yang Mei, Yiru Zhang, Kazuo Yamamoto, +3

Proceedings of the National Academy of Sciences

MitophagyApoptosisImmunologyCell DeathChromosome 10 +18

Cucurbitacin B inhibits STAT3 and the Raf/MEK/ERK pathway in leukemia cell line K562

Kin Chan, Kwan Li, Shiu Lam Liu, +3

Cancer Letters

Raf/mek/erk PathwayCell SignalingMedicineReceptor Tyrosine KinaseImmunology +5

Chaperone-mediated autophagy prevents apoptosis by degrading BBC3/PUMA

Wei Xie, Lei Zhang, Haifeng Jiao, +7

Autophagy

MitophagyApoptosisImmunologyCell DeathCell Death Mechanisms +17

TRIM39 regulates cell cycle progression and DNA damage responses via stabilizing p21

Lei Zhang, Yang Mei, Nai Yang Fu, +7

Proceedings of the National Academy of Sciences

MicroRNA‑195 triggers neuroinflammation in Parkinson's disease in a Rho‑associated kinase�1‑dependent manner

Yi Ren, Huajie Li, Wei Xie, +2

Molecular Medicine Reports

Mir‑195 MimicsImmunologyInnate ImmunityImmune SystemMicroglia Activation +26

HDAC6 regulates antibody-dependent intracellular neutralization of viruses via deacetylation of TRIM21

Songbo Xie, Linlin Zhang, Dan Dong, +7

Journal of Biological Chemistry

ENKD1 promotes CP110 removal through competing with CEP97 to initiate ciliogenesis

Ting Song, Yunfan Yang, Peng Zhou, +10

EMBO Reports

Signal TransductionSignaling PathwayCell RegulationMolecular RegulationMolecular Biology +6

The tumor suppressor CYLD controls epithelial morphogenesis and homeostasis by regulating mitotic spindle behavior and adherens junction assembly

Wei Xie, Yunfan Yang, Siqi Gao, +5

Journal of genetics and genomics/Journal of Genetics and Genomics

Developmental BiologySignaling PathwayCell DivisionCell RegulationMedicine +10

ENKD1 promotes epidermal stratification by regulating spindle orientation in basal keratinocytes

Tao Zhong, Xiaofan Wu, Wei Xie, +8

Cell Death and Differentiation

Spindle OrientationSkin DevelopmentBasal KeratinocytesCell DivisionCutaneous Biology +5