Harikrishnan M. Kurup

Selective inhibition of APOBEC3 enzymes by single-stranded DNAs containing 2′-deoxyzebularine

Fareeda M. Barzak, Stefan Harjes, Maksim V. Kvach et al. · Organic & Biomolecular Chemistry · 2019 · 37 citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +13

Structure-guided inhibition of the cancer DNA-mutating enzyme APOBEC3A

Stefan Harjes, Harikrishnan M. Kurup, Amanda E. Rieffer et al. · Nature Communications · 2023 · 26 citations · Full text

Life Sciences, Oncology, Pharmacology +16

Differential Inhibition of APOBEC3 DNA‐Mutator Isozymes by Fluoro‐ and Non‐Fluoro‐Substituted 2′‐Deoxyzebularine Embedded in Single‐Stranded DNA

Maksim V. Kvach, Fareeda M. Barzak, Stefan Harjes et al. · ChemBioChem · 2019 · 24 citations · Full text

Medicine, Molecular Biology, Pharmacology +9

Design, Synthesis, and Evaluation of a Cross-Linked Oligonucleotide as the First Nanomolar Inhibitor of APOBEC3A

Harikrishnan M. Kurup, Maksim V. Kvach, Stefan Harjes et al. · Biochemistry · 2022 · 12 citations · Full text

Medicine, Molecular Biology, Oncology +16