Danda Chapagai

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Active since

2020

Affiliations

University of South Carolina(Current)

Saint John's Health Center

Danda Chapagai is an author at University of South Carolina specializing in polo-like kinase inhibitors, drug discovery, and polo-like kinase inhibition.

ORCID

Publications per year

2020–2023

Publications

Nonpeptidic, Polo-Box Domain-Targeted Inhibitors of PLK1 Block Kinase Activity, Induce Its Degradation and Target-Resistant Cells

Danda Chapagai, Gurusankar Ramamoorthy, Jessy Varghese et al. · Journal of Medicinal Chemistry · 2021 · 16 citations · Full text

Medicine, Oncology, Pharmacology +14

Peptidomimetic Polo‐Box‐Targeted Inhibitors that Engage PLK1 in Tumor Cells and Are Selective against the PLK3 Tumor Suppressor

Merissa Baxter, Danda Chapagai, Sandra Craig et al. · ChemMedChem · 2020 · 13 citations · Full text

Pharmacy, Oncology, Pharmacology +17

Structure-activity and mechanistic studies of non-peptidic inhibitors of the PLK1 polo box domain identified through REPLACE

Sandra Craig, Merissa Baxter, Danda Chapagai et al. · European Journal of Medicinal Chemistry · 2021 · 11 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12

Structural Basis for Variations in Polo-like Kinase 1 Conformation and Intracellular Stability Induced by ATP-Competitive and Novel Noncompetitive Abbapolin Inhibitors

Danda Chapagai, George Merhej, Campbell McInnes et al. · ACS Chemical Biology · 2023 · 11 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

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