Silencing of OB-RGRP in mouse hypothalamic arcuate nucleus increases leptin receptor signaling and prevents diet-induced obesity

Cyril Couturier, Chamsy Sarkis, Karin Séron, +11

Proceedings of the National Academy of Sciences

Prevents Diet-induced ObesityInsulin SignalingGastrointestinal Peptide HormoneObesityMetabolic Syndrome +17

Homozygous deletion of an 80 kb region comprising part of DNAJC6 and LEPR genes on chromosome 1P31.3 is associated with early onset obesity, mental retardation and epilepsy

Virginie Vauthier, Sylvie Jaillard, Hubert Journel, +3

Molecular Genetics and Metabolism

TASOR epigenetic repressor cooperates with a CNOT1 RNA degradation pathway to repress HIV

Roy Matkovic, Marina Morel, Sophie Lanciano, +9

Nature Communications

Endospanins Regulate a Postinternalization Step of the Leptin Receptor Endocytic Pathway

Karin Séron, Cyril Couturier, Sandrine Belouzard, +12

Journal of Biological Chemistry

Improved donor/acceptor BRET couples for monitoring β‐arrestin recruitment to G protein‐coupled receptors

Maud Kamal, Marcel Marquez, Virginie Vauthier, +4

Biotechnology Journal

EngineeringMolecular BiologyRluc8/rgfp CouplesBetaarr AssaysBioluminescence +14

Endospanin 1 silencing in the hypothalamic arcuate nucleus contributes to sustained weight loss of high fat diet obese mice

Virginie Vauthier, T.D. Swartz, P Chen, +6

Gene Therapy

ObesityMetabolic SyndromeEnergy HomeostasisGastrointestinal Peptide HormoneAppetite Control +10

Design and validation of a homogeneous time-resolved fluorescence-based leptin receptor binding assay

Virginie Vauthier, Carine Derviaux, Najim Douayry, +4

Analytical Biochemistry

BiochemistryMedicinePeptide LibraryBioanalysisReceptor (Biochemistry) +5

Structural analogues of roscovitine rescue the intracellular traffic and the function of ER-retained ABCB4 variants in cell models

Virginie Vauthier, Amel Ben Saad, Jonathan Elie, +8

Scientific Reports

Endospanin1 affects oppositely body weight regulation and glucose homeostasis by differentially regulating central leptin signaling

Virginie Vauthier, Clara Roujeau, Patty Chen, +11

Molecular Metabolism

Effect of CFTR correctors on the traffic and the function of intracellularly retained ABCB4 variants

Amel Ben Saad, Virginie Vauthier, Ágota Tóth, +13

Liver International