Oscar Hernandez‐Alba

An Online Four-Dimensional HIC×SEC-IM×MS Methodology for Proof-of-Concept Characterization of Antibody Drug Conjugates

Anthony Ehkirch, Valentina D’Atri, Florent Rouvière et al. · Analytical Chemistry · 2017 · 98 citations · Full text

Engineering, Quantitative Pharmacology, Biomedical Engineering +20

Hyphenation of size exclusion chromatography to native ion mobility mass spectrometry for the analytical characterization of therapeutic antibodies and related products

Anthony Ehkirch, Oscar Hernandez‐Alba, Olivier Colas et al. · Journal of Chromatography B · 2018 · 88 citations · Full text

Immunology, Ion Mobility Spectrometry, Size Exclusion Chromatography +16

A Novel Online Four-Dimensional SEC×SEC-IM×MS Methodology for Characterization of Monoclonal Antibody Size Variants

Anthony Ehkirch, Alexandre Goyon, Oscar Hernandez‐Alba et al. · Analytical Chemistry · 2018 · 63 citations

Engineering, Immunology, Biological Mass Spectrometry +22

Insights from native mass spectrometry approaches for top- and middle- level characterization of site-specific antibody-drug conjugates

Thomas Botzanowski, Stéphane Erb, Oscar Hernandez‐Alba et al. · mAbs · 2017 · 61 citations · Full text

Drug Target, Biological Mass Spectrometry, Medicinal Chemistry +21

Native Mass Spectrometry, Ion Mobility, and Collision-Induced Unfolding for Conformational Characterization of IgG4 Monoclonal Antibodies

Oscar Hernandez‐Alba, Elsa Wagner‐Rousset, Alain Beck et al. · Analytical Chemistry · 2018 · 59 citations · Full text

Immunocytochemical Technique, Immunology, Molecular Biology +17