Dimitri Topalis

ST-246 is a key antiviral to inhibit the viral F13L phospholipase, one of the essential proteins for orthopoxvirus wrapping

Sophie Duraffour, Marı́a M. Lorenzo, Gudrun Zöller et al. · Journal of Antimicrobial Chemotherapy · 2015 · 110 citations · Full text

Crystal structure of poxvirus thymidylate kinase: An unexpected dimerization has implications for antiviral therapy

Christophe Caillat, Dimitri Topalis, Luigi A. Agrofoglio et al. · Proceedings of the National Academy of Sciences · 2008 · 81 citations · Full text

Crystal Structure, Viral Replication, Synthetic Virology +19

<i>In Vitro</i> -Selected Drug-Resistant Varicella-Zoster Virus Mutants in the Thymidine Kinase and DNA Polymerase Genes Yield Novel Phenotype-Genotype Associations and Highlight Differences between Antiherpesvirus Drugs

Graciela Andreï, Dimitri Topalis, Pierre Fiten et al. · Journal of Virology · 2011 · 59 citations · Full text

Novel Antiviral C5-Substituted Pyrimidine Acyclic Nucleoside Phosphonates Selected as Human Thymidylate Kinase Substrates

Dimitri Topalis, Ugo Pradère, Vincent Roy et al. · Journal of Medicinal Chemistry · 2010 · 57 citations

Substrate specificity of vaccinia virus thymidylate kinase

Dimitri Topalis, Bruno Collinet, Cécile Gasse et al. · FEBS Journal · 2005 · 47 citations · Full text

Viral Replication, Molecular Virology, Synthetic Virology +14