Natasha Zarich

Aplidin® induces JNK-dependent apoptosis in human breast cancer cells via alteration of glutathione homeostasis, Rac1 GTPase activation, and MKP-1 phosphatase downregulation

Laura González-Santiago, Yajaira Suárez, Natasha Zarich et al. · Cell Death and Differentiation · 2006 · 83 citations

Life Sciences, Cell Biology, Oncology +17

Grb2 Is a Negative Modulator of the Intrinsic Ras-GEF Activity of hSos1

Natasha Zarich, José Luís Oliva, Natalia Martínez et al. · Molecular Biology of the Cell · 2006 · 54 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15

Plitidepsin Has a Dual Effect Inhibiting Cell Cycle and Inducing Apoptosis via Rac1/c-Jun NH2-Terminal Kinase Activation in Human Melanoma Cells

María José Muñoz-Alonso, Laura González-Santiago, Natasha Zarich et al. · Journal of Pharmacology and Experimental Therapeutics · 2007 · 48 citations

Medicine, Oncology, Pharmacology +17

Discovery of Mitogen-Activated Protein Kinase-Interacting Kinase 1 Inhibitors by a Comprehensive Fragment-Oriented Virtual Screening Approach

Julen Oyarzábal, Natasha Zarich, María I. Albarrán et al. · Journal of Medicinal Chemistry · 2010 · 35 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Potentiation of tumor formation by topical administration of 15-deoxy-Δ 12,14 -prostaglandin J 2 in a model of skin carcinogenesis

Olga Millán, Daniel Rico, Héctor Peinado et al. · Carcinogenesis · 2005 · 34 citations

Medicine, Oncology, Pharmacology +12