N Mullooly

Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes

Seth L. Masters, Aisling Dunne, Shoba Subramanian et al. · Nature Immunology · 2010 · 1.3K citations · Full text

Inflammation, Autoimmune Disease, Diabetes +13

CGRP, adrenomedullin and adrenomedullin 2 display endogenous GPCR agonist bias in primary human cardiovascular cells

Ashley Clark, N Mullooly, Dewi Safitri et al. · Communications Biology · 2021 · 32 citations · Full text

High Seeding Density Induces Local Hypoxia and Triggers a Proinflammatory Response in Isolated Human Islets

Daniel Brandhorst, Heide Brandhorst, N Mullooly et al. · Cell Transplantation · 2016 · 19 citations · Full text

Isolated Pancreatic Islets, Cell Culture, Cellular Physiology +16

Elevated levels of branched‐chain amino acids have little effect on pancreatic islet cells, but <scp>l</scp>‐arginine impairs function through activation of the endoplasmic reticulum stress response

N Mullooly, Wendy Vernon, David M. Smith et al. · Experimental Physiology · 2013 · 17 citations

Various Amino Acids, Insulin Signaling, Gastrointestinal Peptide Hormone +20