The actin binding site of thymosin beta 4 mapped by mutational analysis.

Marleen Van Troys, Daisy Dewitte, Marc Goethals, +3

The EMBO Journal

Protein FunctionMolecular PhysiologySignal TransductionMutational AnalysisMolecular Regulation +9

Mutational analysis of human profilin I reveals a second PI(4,5)-P2 binding site neighbouring the poly(L-proline) binding site

Anja Lambrechts, Veronique Jonckheere, Daisy Dewitte, +2

BMC Biochemistry

Analogous F-actin Binding by Cofilin and Gelsolin Segment 2 Substantiates Their Structural Relationship

Marleen Van Troys, Daisy Dewitte, Jean‐Luc Verschelde, +3

Journal of Biological Chemistry

TetraThymosinβ Is Required for Actin Dynamics in<i>Caenorhabditis elegans</i>and Acts via Functionally Different Actin-binding Repeats

Marleen Van Troys, Kanako Ono, Daisy Dewitte, +5

Molecular Biology of the Cell

Molecular RegulationMolecular BiologyFilament Barbed EndsCytoskeletonCaenorhabditis Elegans +17

The Competitive Interaction of Actin and PIP₂with Actophorin Is Based on Overlapping Target Sites:  Design of a Gain-of-Function Mutant

Marleen Van Troys, Daisy Dewitte, Jean‐Luc Verschelde, +3

Biochemistry

A Phage Display Technique for a Fast, Sensitive, and Systematic Investigation of Protein–Protein Interactions

Stefaan Rossenu, Daisy Dewitte, Joël Vandekerckhove, +1

Journal of Protein Chemistry

Protein ChemistryProtein–protein InteractionsBiochemistryNatural SciencesBiomolecular Analysis +10

Unbalancing the Phosphatidylinositol-4,5-bisphosphate–Cofilin Interaction Impairs Cell Steering

Shirley Leyman, Mazen Sidani, Laila Ritsma, +10

Molecular Biology of the Cell

Cofilin ActivationCytoskeletonCellular PhysiologySignaling PathwayCell Regulation +15

A Phage Display-based Method for Determination of Relative Affinities of Mutants

Stefaan Rossenu, Shirley Leyman, Daisy Dewitte, +5

Journal of Biological Chemistry

Evidence for an actin binding helix in gelsolin segment 2; have homologous sequences in segments 1 and 2 of gelsolin evolved to divergent actin binding functions?

Marleen Van Troys, Daisy Dewitte, Marc Goethals, +2

FEBS Letters

Identification of the PXW Sequence as a Structural Gatekeeper of the Headpiece C-terminal Subdomain Fold

Wim Vermeulen, Marleen Van Troys, David Bourry, +7

Journal of Molecular Biology

Pxw SequenceStructural BiologyMolecular BiologyStructural Gatekeeper