Lee Burns

Effect of gastric pH on the pharmacokinetics of a bcs class II compound in dogs: Utilization of an artificial stomach and duodenum dissolution model and gastroplus,™ simulations to predict absorption

Shobha Bhattachar, E.J. Perkins, Jeffrey S. Tan et al. · Journal of Pharmaceutical Sciences · 2011 · 61 citations

Gastric Ph, Artificial Stomach, Pharmacokinetic Modeling +8

Abstract 1259: Preclinical characterization of LY3537982, a novel, highly selective and potent KRAS-G12C inhibitor

Sheng-Bin Peng, Chong Si, Youyan Zhang et al. · Cancer Research · 2021 · 41 citations

Drug Target, Molecular Biology, Pharmacotherapy +23

Pharmacokinetics of oral and intravenous indomethacin in preterm infants.

RameshM Bhat, D. Vidyasagar, Edward A. Fisher et al. · PubMed · 1980 · 27 citations

Drug Safety, Plasma Half-life, Neonatology +12

Assessment of In Vivo Clinical Product Performance of a Weak Basic Drug by Integration of In Vitro Dissolution Tests and Physiologically Based Absorption Modeling

Xuan Ding, Ivelina Gueorguieva, James A. Wesley et al. · The AAPS Journal · 2015 · 18 citations · Full text

Engineering, Preclinical Drug Evaluation, Medicine +12

Peptide Isolation via Spray Drying: Particle Formation, Process Design and Implementation for the Production of Spray Dried Glucagon

Frederik Doerr, Lee Burns, Becky Lee et al. · Pharmaceutical Research · 2020 · 14 citations · Full text