Aarti Sharma

ALS-associated mutant FUS induces selective motor neuron degeneration through toxic gain of function

Aarti Sharma, Alexander K. Lyashchenko, Lei Lü et al. · Nature Communications · 2016 · 329 citations · Full text

The C9ORF72 GGGGCC expansion forms RNA G-quadruplex inclusions and sequesters hnRNP H to disrupt splicing in ALS brains

Erin G. Conlon, Lei Lü, Aarti Sharma et al. · eLife · 2016 · 284 citations · Full text

Hypoexcitability precedes denervation in the large fast-contracting motor units in two unrelated mouse models of ALS

María de Lourdes Martínez-Silva, Rebecca D Imhoff-Manuel, Aarti Sharma et al. · eLife · 2018 · 160 citations · Full text

Motoneuron Degeneration, Amyotrophic Lateral Sclerosis, Health Sciences +15

A role for complexes of survival of motor neurons (SMN) protein with gemins and profilin in neurite-like cytoplasmic extensions of cultured nerve cells

Aarti Sharma, Anja Lambrechts, Le Hao et al. · Experimental Cell Research · 2005 · 135 citations

Developmental Biology, Neurite-like Cytoplasmic Extensions, Motor Neurons +7

Gamma motor neurons survive and exacerbate alpha motor neuron degeneration in ALS

Mélanie Lalancette–Hébert, Aarti Sharma, Alexander K. Lyashchenko et al. · Proceedings of the National Academy of Sciences · 2016 · 111 citations · Full text

Motor Dysfunction, Motor Control Disorders, Motor Neuron Disease +24