John Chu

Commensal bacteria make GPCR ligands that mimic human signalling molecules

Louis Cohen, Daria Esterházy, Seong-Hwan Kim et al. · Nature · 2017 · 464 citations

G Protein-coupled Receptor, Bacteriology, Molecular Biology +3

Discovery of MRSA active antibiotics using primary sequence from the human microbiome

John Chu, Xavier Vila‐Farrés, Daigo Inoyama et al. · Nature Chemical Biology · 2016 · 192 citations · Full text

Antimicrobial Susceptibility, Health Sciences, Antibiotics +11

Functional metagenomic discovery of bacterial effectors in the human microbiome and isolation of commendamide, a GPCR G2A/132 agonist

Louis Cohen, Hahk‐Soo Kang, John Chu et al. · Proceedings of the National Academy of Sciences · 2015 · 187 citations · Full text

Synthetic-Bioinformatic Natural Product Antibiotics with Diverse Modes of Action

John Chu, Bimal Koirala, Nicholas Forelli et al. · Journal of the American Chemical Society · 2020 · 55 citations · Full text

Antimicrobials Inspired by Nonribosomal Peptide Synthetase Gene Clusters

Xavier Vila‐Farrés, John Chu, Daigo Inoyama et al. · Journal of the American Chemical Society · 2017 · 47 citations · Full text

Bioorganic Chemistry, Engineering, Peptide Engineering +17