Alex Koufos

Loss of heterozygosity in three embryonal tumours suggests a common pathogenetic mechanism

Alex Koufos, Marc F. Hansen, Neal G. Copeland et al. · Nature · 1985 · 547 citations

Developmental Biology, Somatic Variant, Tumor Heterogeneity +11

Loss of alleles at loci on human chromosome 11 during genesis of Wilms' tumour

Alex Koufos, Mark Hansen, Beatrice C. Lampkin et al. · Nature · 1984 · 532 citations

Cytogenetics, Genetic Disorder, Genetics +8

Familial Wiedemann-Beckwith syndrome and a second Wilms tumor locus both map to 11p15.5.

Alex Koufos, Paul E. Grundy, Kenneth Morgan et al. · PubMed · 1989 · 455 citations

Osteosarcoma and retinoblastoma: a shared chromosomal mechanism revealing recessive predisposition.

Mark Hansen, Alex Koufos, Brenda L. Gallie et al. · Proceedings of the National Academy of Sciences · 1985 · 420 citations · Full text

Tumoral Pathology, Somatic Variant, Tumor Heterogeneity +13

Familial predisposition to Wilms' tumour does not map to the short arm of chromosome 11

Paul E. Grundy, Alex Koufos, Kenneth Morgan et al. · Nature · 1988 · 251 citations

Familial Predisposition, Chromatin, Short Arm +10