Jian Wu

Structural basis for activity regulation of MLL family methyltransferases

Yanjing Li, Jianming Han, Yuebin Zhang et al. · Nature · 2016 · 246 citations · Full text

Transcriptional Regulation, Biochemistry, Activity Regulation +7

Three flavonoids targeting the β‐hydroxyacyl‐acyl carrier protein dehydratase from <i>Helicobacter pylori</i>: Crystal structure characterization with enzymatic inhibition assay

Liang Zhang, Yunhua Kong, Dalei Wu et al. · Protein Science · 2008 · 160 citations · Full text

Structural basis of ligand recognition and self-activation of orphan GPR52

Xi Lin, Mingyue Li, Niandong Wang et al. · Nature · 2020 · 155 citations

Biochemistry, G Protein-coupled Receptor, Medicine +8

MOF as an evolutionarily conserved histone crotonyltransferase and transcriptional activation by histone acetyltransferase-deficient and crotonyltransferase-competent CBP/p300

Xiaoguang Liu, Wei Wei, Yuting Liu et al. · Cell Discovery · 2017 · 147 citations · Full text

SLX4 Assembles a Telomere Maintenance Toolkit by Bridging Multiple Endonucleases with Telomeres

Bingbing Wan, Jinhu Yin, Kent Horvath et al. · Cell Reports · 2013 · 116 citations · Full text