The Ancient Drug Salicylate Directly Activates AMP-Activated Protein Kinase

Simon A. Hawley, Morgan D. Fullerton, Fiona A. Ross, +11

Science

Signal TransductionOxysterolBiochemistryAmp-activated Protein KinaseMedicine +12

Increased Sarcoplasmic Reticulum Calcium Leak but Unaltered Contractility by Acute CaMKII Overexpression in Isolated Rabbit Cardiac Myocytes

Michael Kohlhaas, Tong Zhang, Tim Seidler, +8

Circulation Research

Cardiac MuscleCa2+ Spark FrequencyCellular PhysiologyMuscle PhysiologyCa2+ Transients +14

GFAT1 phosphorylation by AMPK promotes VEGF-induced angiogenesis

Darya Zibrova, Franck Vandermoere, Olga Göransson, +9

Biochemical Journal

Oxidative Glucose Metabolism Promotes Senescence in Vascular Endothelial Cells

Leonie Karoline Stabenow, Darya Zibrova, Claudia Ender, +5

Cells

AgingMitochondrial DysfunctionMetabolic RemodelingVascular Endothelial CellsOxidative Stress +14

Overexpression of FK-506–Binding Protein 12.0 Modulates Excitation–Contraction Coupling in Adult Rabbit Ventricular Cardiomyocytes

Tim Seidler, Christopher M. Loughrey, Darya Zibrova, +4

Circulation Research

Cardiac MuscleCardiac Excitation-contraction CouplingCellular PhysiologyFk-506–binding Protein 12.0Cell Signaling +18

Normalization of Prandial Blood Glucose and Improvement of Glucose Tolerance by Liver-Specific Inhibition of SH2 Domain–Containing Inositol Phosphatase 2 (SHIP2) in Diabetic KKAy Mice

Rolf Grempler, Darya Zibrova, Corinna Schoelch, +3

Diabetes

Prandial Blood GlucoseGlucose ToleranceInsulin SignalingMetabolic SyndromeLiver-specific Inhibition +19

Hyperglycemia-induced endothelial dysfunction is alleviated by thioredoxin mimetic peptides through the restoration of VEGFR-2-induced responses and improved cell survival

Pia Hemling, Darya Zibrova, Jasmin Strutz, +7

International Journal of Cardiology

InflammationMetabolic SyndromeHyperglycemia-induced Endothelial DysfunctionAtherosclerosisMedicine +12

Inhibition of the interaction between protein phosphatase 1 glycogen-targeting subunit and glycogen phosphorylase increases glycogen synthesis in primary rat hepatocytes

Darya Zibrova, Rolf Grempler, Rüdiger Streicher, +1

Biochemical Journal

Protein kinase A negatively regulates VEGF-induced AMPK activation by phosphorylating CaMKK2 at serine 495

Katrin Spengler, Darya Zibrova, Angela Woods, +4

Biochemical Journal

ImmunologyCell GrowthCellular PhysiologyAngiogenesisSignaling Pathway +18