Demetrios Kalaitzidis

Rapamycin reverses hypertrophic cardiomyopathy in a mouse model of LEOPARD syndrome–associated PTPN11 mutation

Talita Miguel Marin, Kimberly Keith, Benjamin Davies et al. · Journal of Clinical Investigation · 2011 · 277 citations · Full text

Medicine, Cardiology, Genetics +16

AKT/FOXO Signaling Enforces Reversible Differentiation Blockade in Myeloid Leukemias

Stephen M. Sykes, Steven Lane, Lars Bullinger et al. · Cell · 2011 · 256 citations

Medicine, Molecular Biology, Oncology +12

Genetic and Pharmacologic Inhibition of β-Catenin Targets Imatinib-Resistant Leukemia Stem Cells in CML

Florian H. Heidel, Lars Bullinger, Zhaohui Feng et al. · Cell stem cell · 2012 · 225 citations · Full text

Medicine, Oncology, Pharmacology +11

mTOR Complex 1 Plays Critical Roles in Hematopoiesis and Pten-Loss-Evoked Leukemogenesis

Demetrios Kalaitzidis, Stephen M. Sykes, Zhu Wang et al. · Cell stem cell · 2012 · 198 citations · Full text

Life Sciences, Hematology, Molecular Biology +15

Depletion of Jak2V617F myeloproliferative neoplasm-propagating stem cells by interferon-α in a murine model of polycythemia vera

Ann Mullally, Claudia Bruedigam, Luke Poveromo et al. · Blood · 2013 · 173 citations · Full text

Life Sciences, Hematology, Immunology +13