Alicia D’Souza

Exercise training reduces resting heart rate via downregulation of the funny channel HCN4

Alicia D’Souza, Annalisa Bucchi, Anne Berit Johnsen et al. · Nature Communications · 2014 · 264 citations · Full text

Viewpoint: Is the resting bradycardia in athletes the result of remodeling of the sinoatrial node rather than high vagal tone?

Mark R. Boyett, Alicia D’Souza, Henggui Zhang et al. · Journal of Applied Physiology · 2013 · 108 citations

Cardiac Muscle, Electrophysiological Evaluation, Kinesiology +11

Targeting miR-423-5p Reverses Exercise Training–Induced HCN4 Channel Remodeling and Sinus Bradycardia

Alicia D’Souza, Charles M. Pearman, Yanwen Wang et al. · Circulation Research · 2017 · 107 citations · Full text

Tenecteplase versus standard of care for minor ischaemic stroke with proven occlusion (TEMPO-2): a randomised, open label, phase 3 superiority trial

Shelagh B. Coutts, Sandeep Ankolekar, Ramana Appireddy et al. · The Lancet · 2024 · 101 citations · Full text

Thrombosis, Superiority Trial, Ischemic Stroke +12

A circadian clock in the sinus node mediates day-night rhythms in Hcn4 and heart rate

Alicia D’Souza, Yanwen Wang, Cali Anderson et al. · Heart Rhythm · 2020 · 92 citations · Full text