D. Sène

Autoantibodies against type I IFNs in patients with life-threatening COVID-19

Paul Bastard, Lindsey B. Rosen, Qian Zhang et al. · Science · 2020 · 2.8K citations · Full text

Life Sciences, Immunology, Infectious Diseases +14

Inborn errors of type I IFN immunity in patients with life-threatening COVID-19

Qian Zhang, Paul Bastard, Zhiyong Liu et al. · Science · 2020 · 2.4K citations · Full text

Life Sciences, Immunology, Infectious Diseases +16

Effect of Tocilizumab vs Usual Care in Adults Hospitalized With COVID-19 and Moderate or Severe Pneumonia

Olivier Hermine, Xavier Mariette, Pierre‐Louis Tharaux et al. · JAMA Internal Medicine · 2020 · 777 citations · Full text

Medicine, Infectious Diseases, Pharmacotherapy +14

Regulatory T-Cell Responses to Low-Dose Interleukin-2 in HCV-Induced Vasculitis

David Saadoun, Michèlle Rosenzwajg, Florence Joly et al. · New England Journal of Medicine · 2011 · 746 citations · Full text

Life Sciences, Immunology, Infectious Diseases +17

Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths

Paul Bastard, Adrian Gervais, Jérémie Rosain et al. · Science Immunology · 2021 · 631 citations · Full text

Life Sciences, Immunology, Infectious Diseases +11