Bharathi N. Palanisamy

Mitochondrial impairment in microglia amplifies NLRP3 inflammasome proinflammatory signaling in cell culture and animal models of Parkinson’s disease

Souvarish Sarkar, Emir Malovic, Dilshan S. Harishchandra et al. · npj Parkinson s Disease · 2017 · 269 citations · Full text

Organophosphate pesticide chlorpyrifos impairs STAT1 signaling to induce dopaminergic neurotoxicity: Implications for mitochondria mediated oxidative stress signaling events

Neeraj Singh, Vivek Lawana, Jie Luo et al. · Neurobiology of Disease · 2018 · 114 citations · Full text

Reductive Stress, Biochemistry, Dopaminergic Neurotoxicity +11

Kv1.3 modulates neuroinflammation and neurodegeneration in Parkinson’s disease

Souvarish Sarkar, Hai M. Nguyen, Emir Malovic et al. · Journal of Clinical Investigation · 2020 · 112 citations · Full text

Synaptic Transmission, Kinase Fyn, Cellular Neurobiology +24

Manganese exposure exacerbates progressive motor deficits and neurodegeneration in the MitoPark mouse model of Parkinson’s disease: Relevance to gene and environment interactions in metal neurotoxicity

Monica R. Langley, Shivani Ghaisas, Muhammet Ay et al. · NeuroToxicology · 2017 · 58 citations · Full text

Neurodegenerative Diseases, Environmental Risk Factors, Toxicology +10

MitoPark transgenic mouse model recapitulates the gastrointestinal dysfunction and gut-microbiome changes of Parkinson’s disease

Shivani Ghaisas, Monica R. Langley, Bharathi N. Palanisamy et al. · NeuroToxicology · 2019 · 43 citations · Full text

Neurodegenerative Diseases, Gastrointestinal Dysfunction, Dysbiosis +13