Jana L. Markley

Tetracycline-inactivating enzymes from environmental, human commensal, and pathogenic bacteria cause broad-spectrum tetracycline resistance

Andrew J. Gasparrini, Jana L. Markley, Hirdesh Kumar et al. · Communications Biology · 2020 · 196 citations · Full text

Life Sciences, Microbiology, Molecular Biology +17

Discovery of a Potent Chloroacetamide GPX4 Inhibitor with Bioavailability to Enable Target Engagement in Mice, a Potential Tool Compound for Inducing Ferroptosis <i>In Vivo</i>

John T. Randolph, Matthew J. O’Connor, Fei Han et al. · Journal of Medicinal Chemistry · 2023 · 49 citations

Pharmacy, Medicinal Chemistry, Pharmacology +13

Semisynthetic Analogues of Anhydrotetracycline as Inhibitors of Tetracycline Destructase Enzymes

Jana L. Markley, Luting Fang, Andrew J. Gasparrini et al. · ACS Infectious Diseases · 2019 · 43 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +17

Phosphate‐Tether‐Mediated Ring‐Closing Metathesis for the Preparation of Complex 1,3‐<i>anti</i>‐Diol‐Containing Subunits

Rambabu Chegondi, Soma Maitra, Jana L. Markley et al. · Chemistry - A European Journal · 2013 · 17 citations

Pharmacy, Chemistry, Medicinal Chemistry +16

Stream-lined synthesis of 3-hydroxy-β-lactams: Norrish-Yang type II photocyclizations of β-ketoformamides

Jana L. Markley, Tyler L. Morse, Nigam P. Rath et al. · Tetrahedron · 2018 · 13 citations

Natural Sciences, Medicinal Chemistry, Drug Discovery +11