Xavier Florence

Design, Synthesis, and Pharmacological Evaluation of<i>R/S</i>-3,4-Dihydro-2,2-dimethyl- 6-halo-4-(phenylaminocarbonylamino)-2<i>H</i>-1-benzopyrans:  Toward Tissue-Selective Pancreatic β-Cell<i>K</i>_ATPChannel Openers Structurally Related to (±)-Cromakalim

S. Sebille, David Gall, Pascal De Tullio et al. · Journal of Medicinal Chemistry · 2006 · 36 citations

Natural Sciences, Medicinal Chemistry, Pharmacology +17

Development and validation of a nonaqueous capillary electrophoretic method for the enantiomeric purity determination of a synthetic intermediate of new 3,4-dihydro-2,2-dimethyl-2H-1-benzopyrans using a single-isomer anionic cyclodextrin derivative and an ionic liquid

Anne Rousseau, Xavier Florence, Bernard Pirotte et al. · Journal of Chromatography A · 2010 · 33 citations

Pharmacy, Chemistry, Pharmaceutical Analysis +17

Chloro-Substituted 3-Alkylamino-4<i>H</i>-1,2,4-benzothiadiazine 1,1-Dioxides as ATP-Sensitive Potassium Channel Activators: Impact of the Position of the Chlorine Atom on the Aromatic Ring on Activity and Tissue Selectivity

Bernard Pirotte, Pascal De Tullio, Quynh-Anh Nguyen et al. · Journal of Medicinal Chemistry · 2009 · 28 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +8

Design and synthesis of new potassium channel activators derived from the ring opening of diazoxide: Study of their vasodilatory effect, stimulation of elastin synthesis and inhibitory effect on insulin release

Nafila Bouider, Wassim Fhayli, Zeinab Ghandour et al. · Bioorganic & Medicinal Chemistry · 2015 · 28 citations

Pharmacy, Medicinal Chemistry, Pharmacology +16

Synthesis and activity on rat aorta rings and rat pancreatic β-cells of ring-opened analogues of benzopyran-type potassium channel activators

Smaïl Khelili, Xavier Florence, Mourad Bouhadja et al. · Bioorganic & Medicinal Chemistry · 2008 · 21 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17