Polen Sean

Translational control of the activation of transcription factor NF-κB and production of type I interferon by phosphorylation of the translation factor eIF4E

Barbara Herdy, Maritza Jaramillo, Yuri V. Svitkin et al. · Nature Immunology · 2012 · 131 citations · Full text

Cytokine, Transcriptional Regulation, Signal Transduction +13

Vesicular stomatitis virus oncolysis is potentiated by impairing mTORC1-dependent type I IFN production

Tommy Alain, Xueqing Lun, Yvan Martineau et al. · Proceedings of the National Academy of Sciences · 2010 · 131 citations · Full text

Altered interactions between stem-loop IV within the 5′ noncoding region of coxsackievirus RNA and poly(rC) binding protein 2: Effects on IRES-mediated translation and viral infectivity

Polen Sean, Joseph H. C. Nguyen, Bert L. Semler · Virology · 2009 · 61 citations · Full text

Viral Replication, Molecular Virology, Natural Sciences +10

The linker domain of poly(rC) binding protein 2 is a major determinant in poliovirus cap-independent translation

Polen Sean, Joseph H. C. Nguyen, Bert L. Semler · Virology · 2008 · 42 citations · Full text

Virus Structure, Viral Replication, Linker Domain +10

Active-site mTOR inhibitors augment HSV1-dICP0 infection in cancer cells via dysregulated eIF4E/4E-BP axis

Chadi Zakaria, Polen Sean, Huy‐Dung Hoang et al. · PLoS Pathogens · 2018 · 31 citations · Full text

Viral Replication, Immunology, Rapamycin Complex 1 +17