Scott W. Blume

Mithramycin inhibits SP1 binding and selectively inhibits transcriptional activity of the dihydrofolate reductase gene in vitro and in vivo.

Scott W. Blume, Richard C. Snyder, Ratna B. Ray et al. · Journal of Clinical Investigation · 1991 · 332 citations · Full text

Life Sciences, Genetics, Molecular Biology +13

Mithramycin blocks transcriptional initiation of the c-myc P1 and P2 promoters

Richard C. Snyder, Ratna B. Ray, Scott W. Blume et al. · Biochemistry · 1991 · 122 citations

Life Sciences, Biochemistry, Molecular Biology +13

Triplex formation prevents Sp1 binding to the dihydrofolate reductase promoter.

Jay E. Gee, Scott W. Blume, Richard C. Snyder et al. · Journal of Biological Chemistry · 1992 · 57 citations · Full text

Life Sciences, Genetics, Molecular Biology +16

Alterations in RNA‐binding activities of IRES‐regulatory proteins as a mechanism for physiological variability and pathological dysregulation of IGF‐IR translational control in human breast tumor cells

Zheng Meng, Nateka L. Jackson, Hyoungsoo Choi et al. · Journal of Cellular Physiology · 2008 · 50 citations

Life Sciences, Molecular Biology, Oncology +17

The 5′‐untranslated RNA of the human dhfr minor transcript alters transcription pre‐initiation complex assembly at the major (core) promoter

Scott W. Blume, Zheng Meng, Kedar Shrestha et al. · Journal of Cellular Biochemistry · 2002 · 44 citations

Life Sciences, Genetics, Molecular Biology +17