Nuclear CDKs Drive Smad Transcriptional Activation and Turnover in BMP and TGF-β Pathways

Claudio R. Alarcón, Alexia-Ileana Zaromytidou, Qiaoran Xi, +10

Cell

Transcriptional RegulationDevelopmental BiologySignal TransductionSignaling PathwayCell Regulation +5

Ubiquitin Ligase Nedd4L Targets Activated Smad2/3 to Limit TGF-β Signaling

Sheng Gao, Claudio R. Alarcón, Gopal P. Sapkota, +7

Molecular Cell

Transcriptional RegulationMolecular PhysiologySignal TransductionSignaling PathwayCell Regulation +8

Structural Basis for the Versatile Interactions of Smad7 with Regulator WW Domains in TGF-β Pathways

Eric Aragón, Nina Goerner, Qiaoran Xi, +4

Structure

Protein FunctionMolecular PhysiologySignal TransductionSignaling PathwayMolecular Regulation +7

Conversion from Calcineurin Inhibitor– to Belatacept-Based Maintenance Immunosuppression in Renal Transplant Recipients: A Randomized Phase 3b Trial

Klemens Budde, Rohini Prashar, Hermann Haller, +12

Journal of the American Society of Nephrology

Phase 3, multicentre, randomised, placebo-controlled study evaluating the efficacy and safety of ustekinumab in patients with systemic lupus erythematosus

Ronald van Vollenhoven, Kenneth Kalunian, Thomas Dörner, +11

Annals of the Rheumatic Diseases

miRNA expression patterns in chemoresistant breast cancer tissues

Jianxin Lv, Kai Xia, Pengfei Xu, +10

Biomedicine & Pharmacotherapy

Breast OncologyMirna Expression PatternsBreast CancerSmall RnaMicrorna Detection +4

Dpp-responsive Silencers Are Bound by a Trimeric Mad-Medea Complex

Sheng Gao, Janet Steffen, Allen Laughon

Journal of Biological Chemistry

Perfluorooctanoic acid stimulates breast cancer cells invasion and up-regulates matrix metalloproteinase-2/-9 expression mediated by activating NF-κB

Weidong Zhang, Fengliang Wang, Pengfei Xu, +10

Toxicology Letters

Cancer ResearchBreast OncologyBiochemistryMedicineCancer Cell Biology +8

HLA-DRB1 risk alleles for RA are associated with differential clinical responsiveness to abatacept and adalimumab: data from a head-to-head, randomized, single-blind study in autoantibody-positive early RA

William F. C. Rigby, Jane H. Buckner, S. Louis Bridges, +5

Arthritis Research & Therapy

Air pollution exposure and immunological and systemic inflammatory alterations among schoolchildren in China

Xinwei Li, Xiao Zhang, Zhi‐Qiang Zhang, +8

The Science of The Total Environment

AsthmaAllergyGlobal HealthEnvironmental HealthEnvironmental Epidemiology +9