Concepedia

Trevor J Franklin

TJ

2

Publications

26

Citations

2

H-Index

1997

Active since

Affiliations

AstraZeneca (United Kingdom)(Current)

Trevor J Franklin is an author at AstraZeneca (United Kingdom) specializing in cell death, oxidative stress, and apoptosis.

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Publications per year

1997–1999

2

Publications

2

A novel series of non-nucleoside inhibitors of inosine 5′-monophosphate dehydrogenase with immunosuppressive activity§§Abbreviations: β, coefficient of interaction; DTH, delayed-type hypersensitivity; FBS, foetal bovine serum; IMP, inosine 5′-monophosphate; IMPDH, IMP dehydrogenase; K′i, apparent inhibition constant for compound I; Kii, inhibition constant for effect on intercept of Lineweaver–Burk plots; K′x, apparent inhibition constant for compound X; MFT, mycophenolate mofetil; MTT, 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide; MPA, mycophenolic acid; TCA, trichloroacteic acid (10% w/v); v, velocity; v0, uninhibited velocity; and XMP, xanthosine monophosphate.

Trevor J Franklin, William P. Morris, Vivien N. Jacobs et al. · Biochemical Pharmacology · 1999 · 14 citations

Cell cycle specific induction of HL-60 cell differentiation and apoptosis by mycophenolic acid

Andreas Görtz, Trevor J Franklin, Caroline Dive et al. · Cell Death and Differentiation · 1997 · 12 citations · Full text

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