A new molecular link between defective autophagy and erythroid abnormalities in chorea-acanthocytosis

Francesca Lupo, Elena Tibaldi, Alessandro Mattè, +14

Blood

Lyn-mediated SHP-1 recruitment to CD5 contributes to resistance to apoptosis of B-cell chronic lymphocytic leukemia cells

Elena Tibaldi, Anna Maria Brunati, Francesca Zonta, +7

Leukemia

Hematological MalignancyLyn-mediated Shp-1 RecruitmentApoptosisImmunologyCell Death +5

Lyn sustains oncogenic signaling in chronic lymphocytic leukemia by strengthening SET-mediated inhibition of PP2A

Francesca Zonta, Mario A. Pagano, Livio Trentin, +10

Blood

Cortactin, another player in the Lyn signaling pathway, is over-expressed and alternatively spliced in leukemic cells from patients with B-cell chronic lymphocytic leukemia

Cristina Gattazzo, Veronica Martini, Federica Frezzato, +9

Haematologica

Lyn-mediated procaspase 8 dimerization blocks apoptotic signaling in B-cell chronic lymphocytic leukemia

Francesca Zonta, Mario A. Pagano, Livio Trentin, +9

Blood

Targeted activation of the SHP-1/PP2A signaling axis elicits apoptosis of chronic lymphocytic leukemia cells

Elena Tibaldi, Mario A. Pagano, Federica Frezzato, +11

Haematologica

Leukaemic cells from chronic lymphocytic leukaemia patients undergo apoptosis following microtubule depolymerization and <scp>L</scp>yn inhibition by nocodazole

Federica Frezzato, Valentina Trimarco, Veronica Martini, +13

British Journal of Haematology

ApoptosisCell DeathPathologyCll PatientsCytoskeleton +16

A novel class of selective CK2 inhibitors targeting its open hinge conformation

Andrea Dalle Vedove, Francesca Zonta, Enrico Zanforlin, +9

European Journal of Medicinal Chemistry

Medicinal ChemistryOpen Hinge ConformationDrug TargetBiochemistryNatural Sciences +10

Epigenetic heterogeneity affects the risk of relapse in children with t(8;21)RUNX1-RUNX1T1-rearranged AML

Matteo Zampini, Claudia Tregnago, Valéria Bisio, +13

Leukemia

ChromatinGenome InstabilityEpigenetic HeterogeneityGenetic DisorderEpigenetic Change +5

Interaction between the SH3 domain of Src family kinases and the proline-rich motif of HTLV-1 p13: a novel mechanism underlying delivery of Src family kinases to mitochondria

Elena Tibaldi, Andrea Venerando, Francesca Zonta, +8

Biochemical Journal

Molecular BiologyMitochondrial Localization SignalSignaling PathwayMitochondrial BiogenesisReceptor Tyrosine Kinase +14