Rubben Torella

Elabela/Toddler Is an Endogenous Agonist of the Apelin APJ Receptor in the Adult Cardiovascular System, and Exogenous Administration of the Peptide Compensates for the Downregulation of Its Expression in Pulmonary Arterial Hypertension

Peiran Yang, Cai Read, Rhoda E. Kuc et al. · Circulation · 2017 · 234 citations · Full text

Medicine, Pharmacology, Physiology +16

Design, Characterization, and First-In-Human Study of the Vascular Actions of a Novel Biased Apelin Receptor Agonist

Aimée Brame, Janet J. Maguire, Peiran Yang et al. · Hypertension · 2015 · 156 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Long-Pentraxin 3 Derivative as a Small-Molecule FGF Trap for Cancer Therapy

Roberto Ronca, Arianna Giacomini, Emanuela Di Salle et al. · Cancer Cell · 2015 · 129 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12

Mechanism for priming DNA synthesis by yeast DNA Polymerase α

Rajika L. Perera, Rubben Torella, Sebastian Klinge et al. · eLife · 2013 · 106 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

DeltaDelta neural networks for lead optimization of small molecule potency

José Jiménez-Luna, Laura Pérez‐Benito, Gérard Martinez et al. · Chemical Science · 2019 · 74 citations · Full text

Pharmacy, Medicinal Chemistry, Computational Chemistry +14