Rubben Torella

Elabela/Toddler Is an Endogenous Agonist of the Apelin APJ Receptor in the Adult Cardiovascular System, and Exogenous Administration of the Peptide Compensates for the Downregulation of Its Expression in Pulmonary Arterial Hypertension

Peiran Yang, Cai Read, Rhoda E. Kuc et al. · Circulation · 2017 · 225 citations · Full text

Design, Characterization, and First-In-Human Study of the Vascular Actions of a Novel Biased Apelin Receptor Agonist

Aimée Brame, Janet J. Maguire, Peiran Yang et al. · Hypertension · 2015 · 151 citations · Full text

Heart Failure, Peptide Science, Pharmacotherapy +22

Long-Pentraxin 3 Derivative as a Small-Molecule FGF Trap for Cancer Therapy

Roberto Ronca, Arianna Giacomini, Emanuela Di Salle et al. · Cancer Cell · 2015 · 127 citations · Full text

Cancer Therapy, Novel Therapy, Small-molecule Fgf Trap +11

Mechanism for priming DNA synthesis by yeast DNA Polymerase α

Rajika L. Perera, Rubben Torella, Sebastian Klinge et al. · eLife · 2013 · 104 citations · Full text

DeltaDelta neural networks for lead optimization of small molecule potency

José Jiménez-Luna, Laura Pérez‐Benito, Gerard Martínez-Rosell et al. · Chemical Science · 2019 · 70 citations · Full text

Engineering, Machine Learning, Chemical Analysis +23