Marissa L. Calbert

Targeted inhibition of histone H3K27 demethylation is effective in high-risk neuroblastoma

Timothy L. Lochmann, Krista M. Powell, Jungoh Ham et al. · Science Translational Medicine · 2018 · 105 citations · Full text

Medicine, Molecular Genetics, Oncology +7

Discovery of a small-molecule inhibitor that traps Polθ on DNA and synergizes with PARP inhibitors

William Fried, Mrityunjay Tyagi, Leonid Minakhin et al. · Nature Communications · 2024 · 45 citations · Full text

Life Sciences, Biochemistry, Oncology +17

The Ewing Family of Tumors Relies on BCL-2 and BCL-XL to Escape PARP Inhibitor Toxicity

Daniel A.R. Heisey, Timothy L. Lochmann, Konstantinos V. Floros et al. · Clinical Cancer Research · 2018 · 40 citations

Medicine, Oncology, Pharmacology +15

Polλ promotes microhomology-mediated end-joining

Gurushankar Chandramouly, J.A. Jamsen, Nikita Borisonnik et al. · Nature Structural & Molecular Biology · 2022 · 28 citations · Full text

Life Sciences, Biology, Molecular Biology +6

Polθ promotes the repair of 5′-DNA-protein crosslinks by microhomology-mediated end-joining

Gurushankar Chandramouly, Shuren Liao, Timur Rusanov et al. · Cell Reports · 2021 · 24 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17