Zachary Demko

Preparation of 5-Substituted 1<i>H</i>-Tetrazoles from Nitriles in Water

Zachary Demko, K. Barry Sharpless · The Journal of Organic Chemistry · 2001 · 958 citations

Chemical Engineering, Aromatic Nitriles, Engineering +10

A click chemistry approach to tetrazoles by Huisgen 1,3-dipolar cycloaddition: synthesis of 5-acyltetrazoles from azides and acyl cyanides.

Zachary Demko, K. Barry Sharpless · PubMed · 2002 · 447 citations

Huisgen 1,3-Dipolar Cycloaddition, Click Chemistry Approach, Heterocyclic +5

A Click Chemistry Approach to Tetrazoles by Huisgen 1,3-Dipolar Cycloaddition: Synthesis of 5-Sulfonyl Tetrazoles from Azides and Sulfonyl Cyanides We thank the National Institute of General Medical Sciences, National Institutes of Health (GM-28384), the National Science Foundation (CHE-9985553), the Skaggs Institute for Chemical Biology for a Predoctoral Fellowship (Z.D.), and the W. M. Keck Foundation for financial support. Dedicated to Professor Rolf Huisgen, the pioneer of this large and extremely useful family of reactions.

Zachary Demko, K. Barry Sharpless · Angewandte Chemie International Edition · 2002 · 411 citations

Why Is Tetrazole Formation by Addition of Azide to Organic Nitriles Catalyzed by Zinc(II) Salts?

Fahmi Himo, Zachary Demko, Louis Noodleman et al. · Journal of the American Chemical Society · 2003 · 351 citations

Inorganic Chemistry, Chemical Engineering, Engineering +14

Expanding the scope of noninvasive prenatal testing: detection of fetal microdeletion syndromes

Ronald J. Wapner, Joshua Babiarz, Brynn Levy et al. · American Journal of Obstetrics and Gynecology · 2014 · 332 citations