Elien Roose

Preemptive rituximab prevents long-term relapses in immune-mediated thrombotic thrombocytopenic purpura

Matthieu Jestin, Y. Benhamou, An‐Sofie Schelpe et al. · Blood · 2018 · 160 citations · Full text

Medicine, Hematology, Immunology +13

An open conformation of ADAMTS‐13 is a hallmark of acute acquired thrombotic thrombocytopenic purpura

Elien Roose, An‐Sofie Schelpe, Bérangère S. Joly et al. · Journal of Thrombosis and Haemostasis · 2017 · 91 citations · Full text

Medicine, Biochemistry, Molecular Biology +8

Linker regions and flexibility around the metalloprotease domain account for conformational activation of ADAMTS‐13

Louis Deforche, Elien Roose, Aline Vandenbulcke et al. · Journal of Thrombosis and Haemostasis · 2015 · 76 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +9

Open ADAMTS13, induced by antibodies, is a biomarker for subclinical immune-mediated thrombotic thrombocytopenic purpura

Elien Roose, An‐Sofie Schelpe, Edwige Tellier et al. · Blood · 2020 · 74 citations · Full text

Medicine, Hematology, Pathology +11

ADAMTS13 Gene Mutations Influence ADAMTS13 Conformation and Disease Age-Onset in the French Cohort of Upshaw–Schulman Syndrome

Bérangère S. Joly, Pierre Boisseau, Elien Roose et al. · Thrombosis and Haemostasis · 2018 · 67 citations · Full text

Life Sciences, Genetics, Hematology +5