Inge A.M. de Graaf

Preparation and incubation of precision-cut liver and intestinal slices for application in drug metabolism and toxicity studies

Inge A.M. de Graaf, Peter Olinga, Marina H. de Jager et al. · Nature Protocols · 2010 · 408 citations · Full text

Pharmacy, Pharmacology, Toxicology +10

Carbosilane Dendrimers Loaded with siRNA Targeting Nrf2 as a Tool to Overcome Cisplatin Chemoresistance in Bladder Cancer Cells

Leanne Ambrosio, Monica Argenziano, Marie Angèle Cucci et al. · Antioxidants · 2020 · 98 citations · Full text

Medicine, Oncology, Pharmacology +16

Innovative Methods to Study Human Intestinal Drug Metabolism in Vitro: Precision-Cut Slices Compared with Ussing Chamber Preparations

Esther G. van de Kerkhof, Anna‐Lena Ungell, Åsa Sjöberg et al. · Drug Metabolism and Disposition · 2006 · 97 citations

Medicine, Biochemistry, Pharmacology +17

Adjusting the DNA Interaction and Anticancer Activity of Pt(II) N-Heterocyclic Carbene Complexes by Steric Shielding of the Trans Leaving Group

Julienne K. Muenzner, Tobias Rehm, Bernhard Biersack et al. · Journal of Medicinal Chemistry · 2015 · 84 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Induction of Metabolism and Transport in Human Intestine: Validation of Precision-Cut Slices as a Tool to Study Induction of Drug Metabolism in Human Intestine in Vitro

Esther G. van de Kerkhof, Inge A.M. de Graaf, Anna‐Lena Ungell et al. · Drug Metabolism and Disposition · 2007 · 82 citations

Medicine, Biochemistry, Pharmacology +17