N. Nora Yang

Cas9-specific immune responses compromise local and systemic AAV CRISPR therapy in multiple dystrophic canine models

Chady H. Hakim, Sandeep Kumar, Dennis O. Pérez‐López et al. · Nature Communications · 2021 · 161 citations · Full text

A Five-Repeat Micro-Dystrophin Gene Ameliorated Dystrophic Phenotype in the Severe DBA/2J-mdx Model of Duchenne Muscular Dystrophy

Chady H. Hakim, Nalinda B. Wasala, Xiufang Pan et al. · Molecular Therapy — Methods & Clinical Development · 2017 · 108 citations · Full text

Severe Dba/2j-mdx Model, Skeletal Muscle, Duchenne Muscular Dystrophy +4

AAV CRISPR editing rescues cardiac and muscle function for 18 months in dystrophic mice

Chady H. Hakim, Nalinda B. Wasala, Christopher E. Nelson et al. · JCI Insight · 2018 · 96 citations · Full text

Dual AAV Gene Therapy for Duchenne Muscular Dystrophy with a 7-kb <i>Mini-Dystrophin</i> Gene in the Canine Model

Kasun Kodippili, Chady H. Hakim, Xiufang Pan et al. · Human Gene Therapy · 2017 · 73 citations · Full text

Small molecule inhibition of group I p21-activated kinases in breast cancer induces apoptosis and potentiates the activity of microtubule stabilizing agents

Christy C. Ong, Sarah Gierke, Cameron Pitt et al. · Breast Cancer Research · 2015 · 71 citations · Full text