Alan R. Healy

Structure elucidation of colibactin and its DNA cross-links

Mengzhao Xue, Chung Sub Kim, Alan R. Healy et al. · Science · 2019 · 266 citations

Life Sciences, Biochemistry, Microbiology +16

A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage

Marcus J.G.W. Ladds, Ingeborg M.M. van Leeuwen, Catherine J. Drummond et al. · Nature Communications · 2018 · 92 citations · Full text

Medicine, Oncology, Pharmacology +13

ClbS Is a Cyclopropane Hydrolase That Confers Colibactin Resistance

Prabhanshu Tripathi, Emilee E. Shine, Alan R. Healy et al. · Journal of the American Chemical Society · 2017 · 80 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +7

A Mechanistic Model for Colibactin-Induced Genotoxicity

Alan R. Healy, Herman Nikolayevskiy, Jaymin R. Patel et al. · Journal of the American Chemical Society · 2016 · 77 citations

Life Sciences, Microbiology, Molecular Biology +13

Synthesis and Structure–Activity Analysis of New Phosphonium Salts with Potent Activity against African Trypanosomes

Andrea Taladriz‐Sender, Alan R. Healy, Eddysson J. Flores Pérez et al. · Journal of Medicinal Chemistry · 2012 · 56 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17