Christopher R. Shaler

Influenza Infection Leads to Increased Susceptibility to Subsequent Bacterial Superinfection by Impairing NK Cell Responses in the Lung

Cherrie-Lee Small, Christopher R. Shaler, Sarah McCormick et al. · The Journal of Immunology · 2010 · 221 citations · Full text

Veterinary Medicine, Immunology, Infectious Diseases +17

MAIT cells launch a rapid, robust and distinct hyperinflammatory response to bacterial superantigens and quickly acquire an anergic phenotype that impedes their cognate antimicrobial function: Defining a novel mechanism of superantigen-induced immunopathology and immunosuppression

Christopher R. Shaler, Joshua Choi, Patrick T. Rudak et al. · PLoS Biology · 2017 · 151 citations · Full text

Veterinary Medicine, Immunology, Pathobiology +17

Mechanisms of delayed anti-tuberculosis protection in the lung of parenteral BCG-vaccinated hosts: A critical role of airway luminal T cells

Carly N. Horvath, Christopher R. Shaler, Mangalakumari Jeyanathan et al. · Mucosal Immunology · 2012 · 69 citations · Full text

Life Sciences, Immunology, Infectious Diseases +14

Mucosa-associated invariant T cells infiltrate hepatic metastases in patients with colorectal carcinoma but are rendered dysfunctional within and adjacent to tumor microenvironment

Christopher R. Shaler, Mauro Enrique Tun‐Abraham, Anton Skaro et al. · Cancer Immunology Immunotherapy · 2017 · 67 citations · Full text

Medicine, Immunology, Oncology +16

Psychological stress impairs IL22-driven protective gut mucosal immunity against colonising pathobionts

Christopher R. Shaler, Alexandra A. Parco, Wael Elhenawy et al. · Nature Communications · 2021 · 67 citations · Full text

Life Sciences, Immunology, Pathobiology +17