Kim Journault

Common Human UGT1A Polymorphisms and the Altered Metabolism of Irinotecan Active Metabolite 7-Ethyl-10-hydroxycamptothecin (SN-38)

Jean-François Gagné, Valérie Montminy, Patrick Bélanger et al. · Molecular Pharmacology · 2002 · 341 citations

Medicine, Biochemistry, Pharmacology +14

Stereoselective Conjugation of Oxazepam by Human UDP-Glucuronosyltransferases (UGTs): S-Oxazepam Is Glucuronidated by UGT2B15, While R-Oxazepam Is Glucuronidated by UGT2B7 and UGT1A9

Michael H. Court, Su Duan, Chantal Guillemette et al. · Drug Metabolism and Disposition · 2002 · 171 citations

Medicine, Pharmacokinetics, Pharmacology +13

Influence of Nonsynonymous Polymorphisms of UGT1A8 and UGT2B7 Metabolizing Enzymes on the Formation of Phenolic and Acyl Glucuronides of Mycophenolic Acid

Olivier Bernard, Jelena Tojcic, Kim Journault et al. · Drug Metabolism and Disposition · 2006 · 108 citations

Medicine, Genetics, Pharmacology +17

Regulation of the UGT1A1 bilirubin-conjugating pathway: Role of a new splicing event at the UGT1A locus

Éric Lévesque, Hugo Girard, Kim Journault et al. · Hepatology · 2006 · 95 citations

Life Sciences, Biochemistry, Molecular Biology +12

Genetic diversity at the UGT1 locus is amplified by a novel 3′ alternative splicing mechanism leading to nine additional UGT1A proteins that act as regulators of glucuronidation activity

Hugo Girard, Éric Lévesque, Judith Bellemare et al. · Pharmacogenetics and Genomics · 2007 · 92 citations

Life Sciences, Genetics, Molecular Biology +7