Joy Ogbechi

The Pathogenic Mechanism of the Mycobacterium ulcerans Virulence Factor, Mycolactone, Depends on Blockade of Protein Translocation into the ER

Belinda S. Hall, Kirsti Hill, Michael J. McKenna et al. · PLoS Pathogens · 2014 · 165 citations · Full text

Life Sciences, Molecular Biology, Pathology +17

Inhibition of Sec61-dependent translocation by mycolactone uncouples the integrated stress response from ER stress, driving cytotoxicity via translational activation of ATF4

Joy Ogbechi, Belinda S. Hall, Thomas Sbarrato et al. · Cell Death and Disease · 2018 · 84 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

TNF receptor 2 signaling prevents DNA methylation at the <i>Foxp3</i> promoter and prevents pathogenic conversion of regulatory T cells

Wen-Yi Tseng, Yi-Shu Huang, Felix I. L. Clanchy et al. · Proceedings of the National Academy of Sciences · 2019 · 84 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

Mycolactone-Dependent Depletion of Endothelial Cell Thrombomodulin Is Strongly Associated with Fibrin Deposition in Buruli Ulcer Lesions

Joy Ogbechi, Marie-Thérèse Ruf, Belinda S. Hall et al. · PLoS Pathogens · 2015 · 53 citations · Full text

Medicine, Cell Biology, Pathology +17

Pharmacological modulation of T cell immunity results in long-term remission of autoimmune arthritis

Wen-Yi Tseng, Felix I. L. Clanchy, Louise M. Topping et al. · Proceedings of the National Academy of Sciences · 2021 · 32 citations · Full text

Life Sciences, Immunology, Pharmacology +17