Melville C. Osborne

Reduction in Glucagon Receptor Expression by an Antisense Oligonucleotide Ameliorates Diabetic Syndrome in<i>db/db</i>Mice

Yin Liang, Melville C. Osborne, Brett P. Monia et al. · Diabetes · 2004 · 197 citations

Topiramate is an insulin-sensitizing compound in vivo with direct effects on adipocytes in female ZDF rats

Jason J. Wilkes, Elizabeth A. Nelson, Melville C. Osborne et al. · American Journal of Physiology-Endocrinology and Metabolism · 2004 · 63 citations

Muscle Strips, Insulin Signaling, Obesity +20

A Novel Method for Analysis of Nuclear Receptor Function at Natural Promoters: Peroxisome Proliferator-Activated Receptor γ Agonist Actions on aP2 Gene Expression Detected Using Branched DNA Messenger RNA Quantitation

Thomas P. Burris, Patricia D. Pelton, Lubing Zhou et al. · Molecular Endocrinology · 1999 · 57 citations · Full text

In Vivo Characterization of a Dual Adenosine A_2A/A₁ Receptor Antagonist in Animal Models of Parkinson’s Disease

Brian C. Shook, Stefanie Rassnick, Melville C. Osborne et al. · Journal of Medicinal Chemistry · 2010 · 54 citations · Full text

Dual Adenosine A, Receptor Antagonist, Pharmacotherapy +19

Benzoxazinones as PPARγ Agonists. 2. SAR of the Amide Substituent and In Vivo Results in a Type 2 Diabetes Model

Philip J. Rybczynski, Roxanne E. Zeck, Joseph Dudash et al. · Journal of Medicinal Chemistry · 2003 · 47 citations · Full text

Ap2 Gene, Pharmacotherapy, Ppargamma Agonist Activity +17