Methylation of ribosomal RNA by NSUN5 is a conserved mechanism modulating organismal lifespan

Markus Schosserer, Nadège Minois, Tina B. Angerer, +26

Nature Communications

Small extracellular vesicles and their miRNA cargo are anti-apoptotic members of the senescence-associated secretory phenotype

Lucia Terlecki‐Ζaniewicz, Ingo Lämmermann, Julie Latreille, +12

Aging

ImmunologyCell DeathExtracellular MicrovesiclesSmall Extracellular VesiclesCell Signaling +14

Loss of the ribosomal RNA methyltransferase NSUN5 impairs global protein synthesis and normal growth

Clemens Heissenberger, Lisa Liendl, Fabian Nagelreiter, +20

Nucleic Acids Research

EngineeringRibosomal RnaGeneticsMolecular BiologyGlobal Protein Synthesis +17

High levels of oncomi<scp>R</scp>‐21 contribute to the senescence‐induced growth arrest in normal human cells and its knock‐down increases the replicative lifespan

Hanna Dellago, Barbara Preschitz‐Kammerhofer, Lucia Terlecki‐Ζaniewicz, +12

Aging Cell

AgingImmunologyMirna ArraysCell ProliferationCellular Physiology +19

Organotypic human skin culture models constructed with senescent fibroblasts show hallmarks of skin aging

Regina Weinmüllner, Barbara Zbiral, Adnan Becirovic, +16

npj Aging and Mechanisms of Disease

Tissue EngineeringSkin EquivalentEngineeringAgingBiomedical Engineering +16

Comparability of Raman Spectroscopic Configurations: A Large Scale Cross-Laboratory Study

Shuxia Guo, Claudia Beleites, Ute Neugebauer, +81

Analytical Chemistry

EngineeringSurface-enhanced Raman ScatteringRaman Spectroscopic ConfigurationsChemistrySpectrochemical Analysis +14

Extracellular Vesicles in Human Skin: Cross-Talk from Senescent Fibroblasts to Keratinocytes by miRNAs

Lucia Terlecki‐Ζaniewicz, Vera Pils, Madhusudhan Reddy Bobbili, +18

Journal of Investigative Dermatology

Blocking negative effects of senescence in human skin fibroblasts with a plant extract

Ingo Lämmermann, Lucia Terlecki‐Ζaniewicz, Regina Weinmüllner, +19

npj Aging and Mechanisms of Disease

The ribosomal RNA m5C methyltransferase NSUN-1 modulates healthspan and oogenesis in Caenorhabditis elegans

Clemens Heissenberger, Jarod Rollins, Teresa L. Krammer, +10

eLife

The thiosemicarbazone Me2NNMe2 induces paraptosis by disrupting the ER thiol redox homeostasis based on protein disulfide isomerase inhibition

Sonja Hager, Katharina Korbula, Bjoern Bielec, +14

Cell Death and Disease