Concepedia

John R. Hepler

JR

Statistics

Publications

80

Citations

8.1K

H-Index

44

Active since

1982

Affiliations

Emory University(Current)

University of North Carolina at Chapel Hill

The University of Texas Southwestern Medical Center

National Institutes of Health

National Institute of Environmental Health Sciences

John R. Hepler is an author at Emory University specializing in signal transduction, life sciences, and cell signaling.

ORCID

Publications per year

1982–2023

80

Publications

80

Regulation of Polyphosphoinositide-specific Phospholipase C Activity by Purified G <sub>q</sub>

Alan V. Smrcka, John R. Hepler, Kendall O. Brown et al. · Science · 1991 · 903 citations

, , +14

RGS4 and GAIP are GTPase-activating proteins for G <sub>qα</sub> and block activation of phospholipase Cβ by γ-thio-GTP-G <sub>qα</sub>

John R. Hepler, David M. Berman, Alfred G. Gilman et al. · Proceedings of the National Academy of Sciences · 1997 · 366 citations · Full text

, , +14

Distinct patterns of bidirectional regulation of mammalian adenylyl cyclases.

Ronald Taussig, Wei‐Jen Tang, John R. Hepler et al. · Journal of Biological Chemistry · 1994 · 361 citations · Full text

, , +14

Lipid modifications of G proteins: alpha subunits are palmitoylated.

Maurine E. Linder, Philippa Middleton, John R. Hepler et al. · Proceedings of the National Academy of Sciences · 1993 · 351 citations

, , +9

RGS2/G0S8 is a selective inhibitor of Gqα function

Scott P. Heximer, Ned Watson, Maurine E. Linder et al. · Proceedings of the National Academy of Sciences · 1997 · 347 citations

, , +13

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