Concepedia

John R. Hepler

JR

80

Publications

8.1K

Citations

44

H-Index

1982

Active since

Affiliations

Emory University(Current)

University of North Carolina at Chapel Hill

The University of Texas Southwestern Medical Center

National Institutes of Health

National Institute of Environmental Health Sciences

John R. Hepler is an author at Emory University specializing in medicine, signal transduction, and molecular physiology.

ORCID

Top concepts

Publications per year

1982–2023

80

Publications

80

Regulation of Polyphosphoinositide-specific Phospholipase C Activity by Purified G <sub>q</sub>

Alan V. Smrcka, John R. Hepler, Kendall O. Brown et al. · Science · 1991 · 901 citations

RGS4 and GAIP are GTPase-activating proteins for G <sub>qα</sub> and block activation of phospholipase Cβ by γ-thio-GTP-G <sub>qα</sub>

John R. Hepler, David M. Berman, Alfred G. Gilman et al. · Proceedings of the National Academy of Sciences · 1997 · 366 citations · Full text

Distinct patterns of bidirectional regulation of mammalian adenylyl cyclases.

Ronald Taussig, Wei‐Jen Tang, John R. Hepler et al. · Journal of Biological Chemistry · 1994 · 359 citations · Full text

RGS2/G0S8 is a selective inhibitor of Gqα function

Scott P. Heximer, Ned Watson, Maurine E. Linder et al. · Proceedings of the National Academy of Sciences · 1997 · 346 citations · Full text

Lipid modifications of G proteins: alpha subunits are palmitoylated.

Maurine E. Linder, Philippa Middleton, John R. Hepler et al. · Proceedings of the National Academy of Sciences · 1993 · 346 citations · Full text

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