William R. Foster

Human aminolevulinate synthase structure reveals a eukaryotic-specific autoinhibitory loop regulating substrate binding and product release

H. Bailey, G.A. Bezerra, Jason R. Marcero et al. · Nature Communications · 2020 · 42 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Inhibition of MRN activity by a telomere protein motif

Freddy Khayat, Elda Cannavò, Majedh Alshmery et al. · Nature Communications · 2021 · 34 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Crystal structure and interaction studies of human DHTKD1 provide insight into a mitochondrial megacomplex in lysine catabolism

G.A. Bezerra, William R. Foster, H. Bailey et al. · IUCrJ · 2020 · 25 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

Fragment Screening Reveals Starting Points for Rational Design of Galactokinase 1 Inhibitors to Treat Classic Galactosemia

Sabrina MacKinnon, T. Krojer, William R. Foster et al. · ACS Chemical Biology · 2021 · 15 citations · Full text

Life Sciences, Biochemistry, Medicinal Chemistry +17

Identification of small molecule allosteric modulators of 5,10-methylenetetrahydrofolate reductase (MTHFR) by targeting its unique regulatory domain

G.A. Bezerra, Alexander Holenstein, William R. Foster et al. · Biochimie · 2021 · 12 citations · Full text

Life Sciences, Biochemistry, Pharmacology +16