Petra Gorombei

The proneural gene ASCL1 governs the transcriptional subgroup affiliation in glioblastoma stem cells by directly repressing the mesenchymal gene NDRG1

Ashwin Narayanan, Filippo Gagliardi, Alberto L. Gallotti et al. · Cell Death and Differentiation · 2018 · 57 citations · Full text

Medicine, Molecular Biology, Oncology +17

BCL-2 inhibition with ABT-737 prolongs survival in an NRAS/BCL-2 mouse model of AML by targeting primitive LSK and progenitor cells

Stéphanie Beurlet, Nader Omidvar, Petra Gorombei et al. · Blood · 2013 · 48 citations · Full text

Life Sciences, Molecular Biology, Oncology +14

BCL-2 Inhibitor ABT-737 Effectively Targets Leukemia-Initiating Cells with Differential Regulation of Relevant Genes Leading to Extended Survival in a NRAS/BCL-2 Mouse Model of High Risk-Myelodysplastic Syndrome

Petra Gorombei, Fabien Guidez, Saravanan Ganesan et al. · International Journal of Molecular Sciences · 2021 · 19 citations · Full text

Medicine, Hematology, Oncology +17

GEP analysis validates high risk MDS and acute myeloid leukemia post MDS mice models and highlights novel dysregulated pathways

Laura Guerenne, Stéphanie Beurlet, M.S. Said et al. · Journal of Hematology & Oncology · 2016 · 13 citations · Full text

Life Sciences, Genetics, Molecular Biology +14