Takuji Kakigami

Discovery and pharmacological characterization of N-[2-({2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl}amino)-2-methylpropyl]-2-methylpyrazolo[1,5-a]pyrimidine-6-carboxamide hydrochloride (anagliptin hydrochloride salt) as a potent and selective DPP-IV inhibitor

Noriyasu Kato, Mitsuru Oka, Takayo Murase et al. · Bioorganic & Medicinal Chemistry · 2011 · 87 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +11

Synthesis and pharmacological characterization of potent, selective, and orally bioavailable isoindoline class dipeptidyl peptidase IV inhibitors

Noriyasu Kato, Mitsuru Oka, Takayo Murase et al. · Organic and Medicinal Chemistry Letters · 2011 · 20 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +8

Synthesis and Aldose Reductase Inhibitory Activity of 2-Substituted 6-Fluoro-2,3-dihydrospiro(4H-1-benzopyran-4,4'-imidazolidine) 2',5'-diones.

Ryoichi Unno, Takuji Yamaguchi, T. USUI et al. · Chemical and Pharmaceutical Bulletin · 1994 · 18 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +9

Synthesis and Anti-influenza Virus Activity of Tricyclic Compounds with a Unique Amine Moiety.

Mitsuru Oka, Yoshiro Ishiwata, Noriyuki Iwata et al. · Chemical and Pharmaceutical Bulletin · 2001 · 12 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15