Celia Lafuente

A Novel, Orally Bioavailable Nociceptin Receptor Antagonist, LY2940094, Reduces Ethanol Self-Administration and Ethanol Seeking in Animal Models

Linda M. Rorick‐Kehn, Roberto Ciccocioppo, Conrad J. Wong et al. · Alcoholism Clinical and Experimental Research · 2016 · 60 citations · Full text

Discovery of a Novel Series of Orally Active Nociceptin/Orphanin FQ (NOP) Receptor Antagonists Based on a Dihydrospiro(piperidine-4,7′-thieno[2,3-<i>c</i>]pyran) Scaffold

Miguel A. Toledo, Concepción Pedregal, Celia Lafuente et al. · Journal of Medicinal Chemistry · 2014 · 55 citations · Full text

Receptor Antagonists, Molecular Pain, Nop Receptor +20

Preclinical findings predicting efficacy and side‐effect profile of <scp>LY</scp> 2940094, an antagonist of nociceptin receptors

Jeffrey M. Witkin, Linda M. Rorick‐Kehn, Mark J. Benvenga et al. · Pharmacology Research & Perspectives · 2016 · 31 citations · Full text

Development of LC-MS/MS-Based Receptor Occupancy Tracers and Positron Emission Tomography Radioligands for the Nociceptin/Orphanin FQ (NOP) Receptor

Concepción Pedregal, Elizabeth Joshi, Miguel A. Toledo et al. · Journal of Medicinal Chemistry · 2012 · 28 citations · Full text

Pain Medicine, Neuropathic Pain, Molecular Pain +21

Synthesis of 3a,4-dihydro-3H-[1]benzopyrano[4,3-c]isoxazoles, displaying combined 5-HT uptake inhibiting and α2-adrenoceptor antagonistic activities. Part 2: Further exploration on the cinnamyl moiety

Joaquı́n Pastor, Jesús Alcázar, Rosa M. Álvarez et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 18 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, α2-Adrenoceptor Antagonistic Activities +13