Mitochondrial Dysfunction Is the Focus of Quaternary Ammonium Surfactant Toxicity to Mammalian Epithelial Cells

Ângela Inácio, Gabriel N. Costa, Neuza Domingues, +4

Antimicrobial Agents and Chemotherapy

Mitochondrial DysfunctionLipid PeroxidationApoptosisCell DeathChemical Biology +16

Quaternary ammonium surfactant structure determines selective toxicity towards bacteria: mechanisms of action and clinical implications in antibacterial prophylaxis

Ângela Inácio, Neuza Domingues, Alexandra Nunes, +9

Journal of Antimicrobial Chemotherapy

Cholesterol is Inefficiently Converted to Cholesteryl Esters in the Blood of Cardiovascular Disease Patients

Mathias J. Gerl, Winchil L.C. Vaz, Neuza Domingues, +11

Scientific Reports

Therapeutic properties of VO(dmpp)2 as assessed by in vitro and in vivo studies in type 2 diabetic GK rats

Neuza Domingues, Julien Pelletier, C.‐G. Östenson, +1

Journal of Inorganic Biochemistry

MedicineDiabetesPhysiologyType 2Diabetic Kidney Disease +5

Shotgun mass spectrometry-based lipid profiling identifies and distinguishes between chronic inflammatory diseases

Rune Matthiesen, Chris Lauber, Júlio L. Sampaio, +15

EBioMedicine

1,8-Cineole ameliorates right ventricle dysfunction associated with pulmonary arterial hypertension by restoring connexin43 and mitochondrial homeostasis

Jorge M. Alves-Silva, Mónica Zuzarte, Carla Marques, +11

Pharmacological Research

Unveiling the Interaction of Vanadium Compounds with Human Serum Albumin by Using ¹H STD NMR and Computational Docking Studies

David M. Dias, João Rodrigues, Neuza Domingues, +2

European Journal of Inorganic Chemistry

EngineeringHsa BindersChemistryPharmaceutical ChemistrySmall Molecules +18

Involvement of the p62/NRF2 signal transduction pathway on erythrophagocytosis

Inês B. Santarino, Michelle Viegas, Neuza Domingues, +3

Scientific Reports

In vitro effects of bis(1,2-dimethyl-3-hydroxy-4-pyridinonato)oxidovanadium(IV), or VO(dmpp)2, on insulin secretion in pancreatic islets of type 2 diabetic Goto-Kakizaki rats

Julien Pelletier, Neuza Domingues, M. Margarida C. A. Castro, +1

Journal of Inorganic Biochemistry

Metabolic SyndromePancreatic IsletsBiochemistryMedicinePhysiology +8

Connexin43 promotes exocytosis of damaged lysosomes through actin remodelling

Neuza Domingues, Steve Catarino, Beatriz Cristóvão, +16

The EMBO Journal