Aleksandra Kostina

Network-based screen in iPSC-derived cells reveals therapeutic candidate for heart valve disease

Christina V. Theodoris, Ping Zhou, Lei Liu et al. · Science · 2020 · 101 citations · Full text

Engineering, Heart Valve Disease, Network-based Screen +23

A patterned human primitive heart organoid model generated by pluripotent stem cell self-organization

Brett Volmert, Artem Kiselev, Aniwat Juhong et al. · Nature Communications · 2023 · 86 citations · Full text

Notch-dependent EMT is attenuated in patients with aortic aneurysm and bicuspid aortic valve

Aleksandra Kostina, Vladimir Uspensky, O. B. Irtyuga et al. · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 2016 · 73 citations

Heart Failure, Bicuspid Aortic Valve, Valve Disease +7

Phenotypic and Functional Changes of Endothelial and Smooth Muscle Cells in Thoracic Aortic Aneurysms

Anna Malashicheva, Daria Kostina, Aleksandra Kostina et al. · International Journal of Vascular Medicine · 2016 · 58 citations · Full text

Vascular Disease, Engineering, Bicuspid Aortic Valve +27

Different Notch signaling in cells from calcified bicuspid and tricuspid aortic valves

Aleksandra Kostina, Elena Ignatieva, O. B. Irtyuga et al. · Journal of Molecular and Cellular Cardiology · 2017 · 51 citations

Signal Transduction, Tricuspid Aortic Valves, Physiology +9