Nikos Pagratis

Clinical targeting of HIV capsid protein with a long-acting small molecule

John O. Link, Martin S. Rhee, Winston C. Tse et al. · Nature · 2020 · 392 citations · Full text

Natural Sciences, Human Retrovirus, Immunology +10

Potent 2′-amino-, and 2′-fluoro-2′- deoxyribonucleotide RNA inhibitors of keratinocyte growth factor

Nikos Pagratis, Carol Bell, Ying-Fon Chang et al. · Nature Biotechnology · 1997 · 214 citations

Molecular Biology, Keratinocyte Growth Factor, Antisense Therapy +3

<i>In Vitro</i> Antiviral Activity and Resistance Profile Characterization of the Hepatitis C Virus NS5A Inhibitor Ledipasvir

Guofeng Cheng, Tian Yang, Brian Doehle et al. · Antimicrobial Agents and Chemotherapy · 2016 · 69 citations · Full text

The novel CaMKII inhibitor GS-680 reduces diastolic SR Ca leak and prevents CaMKII-dependent pro-arrhythmic activity

Simon Lebek, A. Plößl, Maria J. Baier et al. · Journal of Molecular and Cellular Cardiology · 2018 · 57 citations

Cardiac Muscle, Cardiomyopathy, Molecular Physiology +6

Identification of Orally Available Naphthyridine Protein Kinase D Inhibitors

Erik L. Meredith, Ophelia Ardayfio, Kimberly Beattie et al. · Journal of Medicinal Chemistry · 2010 · 53 citations · Full text

Medicinal Chemistry, Heart Failure, Biochemistry +11