Gut microbiome influences efficacy of PD-1–based immunotherapy against epithelial tumors

Bertrand Routy, Emmanuelle Le Chatelier, Lisa Derosa, +45

Science

Negative association of antibiotics on clinical activity of immune checkpoint inhibitors in patients with advanced renal cell and non-small-cell lung cancer

Lisa Derosa, Matthew D. Hellmann, Marco Spaziano, +13

Annals of Oncology

Ketogenic diet and ketone bodies enhance the anticancer effects of PD-1 blockade

Gladys Ferrere, Maryam Tidjani Alou, Peng Liu, +25

JCI Insight

Ketogenic DietChemoprevention StrategyPd-1 BlockadeImmunologyImmune Regulation +20

Gut Bacteria Composition Drives Primary Resistance to Cancer Immunotherapy in Renal Cell Carcinoma Patients

Lisa Derosa, Bertrand Routy, Marine Fidelle, +31

European Urology

Antimicrobial Resistance GeneDysbiosisHealth SciencesCancer ImmunosurveillanceImmunology +8

A microbiota-modulated checkpoint directs immunosuppressive intestinal T cells into cancers

Marine Fidelle, Conrad Rauber, Carolina Alves Costa Silva, +63

Science

Intestinal microbiota influences clinical outcome and side effects of early breast cancer treatment

Safae Terrisse, Lisa Derosa, Valerio Iebba, +26

Cell Death and Differentiation

Custom scoring based on ecological topology of gut microbiota associated with cancer immunotherapy outcome

Lisa Derosa, Valerio Iebba, Carolina Alves Costa Silva, +48

Cell

Immune system and intestinal microbiota determine efficacy of androgen deprivation therapy against prostate cancer

Safae Terrisse, Anne‐Gaëlle Goubet, Kousuke Ueda, +34

Journal for ImmunoTherapy of Cancer

Low-dose irradiation of the gut improves the efficacy of PD-L1 blockade in metastatic cancer patients

Jianzhou Chen, Antonin Lévy, Ai-Ling Tian, +58

Cancer Cell

Influence of microbiota-associated metabolic reprogramming on clinical outcome in patients with melanoma from the randomized adjuvant dendritic cell-based MIND-DC trial

Carolina Alves Costa Silva, Gianmarco Piccinno, Déborah Suissa, +22

Nature Communications